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Ephedrine alkaloids are amphetamine-like compounds used in OTC and prescription drugs with potentially lethal stimulant effects on the central nervous system and heart. The FDA has received more than
800 reports of adverse effects associated with use of products containing ephedrine alkaloid since 1994. These serious adverse effects, include hypertension (elevated blood pressure), palpitations (ra
pid heart rate), neurophathy (nerve damage), myopathy (muscle injury), psychosis, stroke, memory loss, heart rate irregularities, insomnia, nervousness, tremors, seizures, heart attacks, and death. Th
e agency has proposed to prohibit the marketing of dietary supplements containing 8 milligrams or more of ephedrine alkaloids per serving.
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Ephedrine is an adrenergic drug that works by stimulating alpha
-and beta receptors thus causing the release of norepinephrine.
-Alpha and beta receptors exist in the sympathetic nervous system,
-(fight or flight) and stimulation causes increased heart rate,
-bronchodilation, and vasoconstriction.
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Ephedrine is the active ingredient in many diet pills and supplements. Many use the name "thermo", "lean" or "fat burner." Brand names include, Metabolife, MeTrim, Herbalife, Adiphen, Thermalean, Lipo
drene, Zymax, Genicil, Patent Lean, Thermoslim, Ultra Lipo Lean, Trim Life, Hydroxy Cut, Xenadrine, Herbal Phen-Fen, Shapefast, Thermoburn, Thyro-slim, Trim Spa, Natural Trim, Thermo-Lift and many oth
ers.
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Since early 1990, the FDA has issued numerous warnings to consumers of diet products and supplements containing Ephedrine, Ephedra or Ma Huang. In fact, in November 1994, the FDA informed Alliance U.S
.A. that its Nature¡¦s Nutritional Formula One posed a potential health hazard and was in violation of federal laws designed to protect the public health and even issued a recall of their products due
to their combination of Ma Huang and caffeine containing Kola Nut. Alliance later removed the caffeine containing Kola Nut and was allowed to continue to sell its new product.
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Recently, the FDA has called for strict limits on the recommended dose and proposed new labeling of products containing ephedrine. The FDA¡¦s proposal would prohibit the marketing of dietary supplement
s containing 8 milligrams or more of ephedrine alkaloids per serving, with warnings against using more than 24 mg per day and using the product for more than SEVEN DAYS. Any such product with claims e
ncouraging short-term excessive intake would be required to list the following statement on its label: ¡§Taking more than the recommended serving may result in heart attack, stroke, seizure or death.¡¨
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These terms are used to refer to the same substance derived from the plant Ephedra. (There are many common names for these evergreen plants, including squaw tea and Mormon tea.) Ephedra is a shrub-lik
e plant that is found in desert regions in central Asia and other parts of the world. The dried greens of the plant are used medicinally. Ephedra is a stimulant containing the herbal form of ephedrine
, an FDA-regulated drug found in over-the-counter asthma medications.
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