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Significant Interactions:

If Nexium is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Nexium with the foll owing:

- Diazepam (Valium)
- Digoxin (Lanoxin)
- Iron salts (Ferro-Sequels)
- Ketoconazole (Nizoral)
- Warfarin (Coumadin)

There's no problem, however, with com bining antacids and Nexium; no unwanted interaction will result.

Overdosage

Any medication taken in excess can have serious consequences. There have been some reports of Nexium overdoses. If you suspect an overdose, seek medical attention immediately.

Symptoms of Ne xium overdose may include:
- Blurred vision, confusion, drowsiness, dry mouth, flushing, headache, nausea, rapid heartbeat, sweating

Why is this medication prescribed?

Nexium is in a class of drugs called proton pump inhibitors. It works by decreasing the amount of acid made in your stomach. Nexium is used to treat your esophagus, the area between your throat and st omach that has become irritated, painful, and swollen from too much acid in your stomach.

It is used to treat heartburn, acid indigestion, sour stomach, and other conditions in which the stom ach makes too much acid. Nexium also is used in combination with antibiotics to treat ulcers.

How to Use

Nexium comes as delayed-release (long-acting) capsule to take by mouth. For inflamed esophagus and other conditions in which the stomach makes too much acid, one capsule is usually taken once a day fo r 4 to 8 weeks. It may be used for up to 6 months after your symptoms have improved.

For ulcers, one capsule is usually taken in combination with antibiotics once a day for 10 days.

Nexium should be swallowed whole and taken at least 1 hour before meals. Nexium may be taken with water, orange juice, apple juice, or yogurt.

What special precautions should I follow?

Other medicines¡XAlthough certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your do or may want to change the dose, or other precautions may be necessary. Tell your health care professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Possible Side Effect

The following side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
-
Abdominal pain; diarrhea; h eadache

Constipation; dryness of mouth; gas; nausea


To Continue

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